The South Texas Blood and Tissue Center is calling you to action to save two sisters’ lives.

They need blood donations to survive and bone marrow to cure their disorder.

“There’s a lot to smile about, I’m alive,” Kyra Crawford said.

Behind Kami and Kyra Crawford’s bright smiles — there’s pain and perseverance.

“I’ve had two strokes and a seizure,” Kyra confessed. “I almost lost my life twice.”

The 17 and 15-year-old sisters share an unbreakable bond: pain, they’ve both felt everyday of their lives since they were born. Both have sickle cell anemia.

“Our body produces sickle blood cells, which are like a crescent, and what happens with sickle cell is sometimes those blood cells get caught in our blood vessels and wherever that happens throughout the body, that’s what causes our pain,” Kami Crawford explained.

Sickle cell is a blood disorder affecting one out of 365 African Americans.

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